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KMID : 0360220070480030438
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Journal of the Korean Ophthalmological Society
2007 Volume.48 No. 3 p.438 ~ p.444
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The Amniotic Membrane Transplantation in Corneal Perforation due to Mooren`s Ulcer
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Kim Moon-Jung
Wee Won-Ryang
Lee Jin-Hak
Kim Mee-Kum
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Abstract
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Purpose: To report patients with corneal perforation with Mooren`s ulcer treated successfully with amniotic membrane transplantation and cryotherapy.
Methods: We performed conjunctival recession, permanent amniotic membrane transplantation, cryotherapy, amniotic membrane patch to treat corneal perforation associated with severe inflammatory Mooren`s ulcer of 4 eyes in 3 patients. We investigated the interval of absence of inflammation, reepithelization over grafted amniotic membrane, and restoration of visual acuity.
Results: The perforated corneal lesion was sealed successfully by the amniotic membrane in 4 eyes. The complete reepithelization over grafted amniotic membrane was achieved 21±2.7 days and complete remission was achieved 94±13.0 days after surgery. There was no recurrence in 3 eyes during 21±2.7 months. A patient who recurred inflammatory impending corneal perforation underwent limbal transplantation with amniotic membrane re-transplantation, which resulted in remission after 13 months. All 3 eyes restored visual acuity Except one who developed cataract.
Conclusions: Amniotic membrane transplantation may be useful in treating corneal perforation with active inflammation in Mooren`s ulcer. J Korean Ophthalmol Soc 48(3):438-444, 2007
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KEYWORD
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Amniotic membrane transplantation, Corneal perforation, Mooren`s ulcer, Reepithelialization
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